Lab news

Yuanbo, Lan, Yuan, and Peien have successfully defended their theses. Congratulations and good luck with their future endeavors! We have also experienced our very first online defense. It was fun......


May 29, 2020





Our paper on OPA1-MGD structure has been published in JCB. It sheds light on its dimerization that is physiologically important and provides an explanation for pathogenic mutations. Congratulations Jinghua!

Link: https://doi.org/10.1083/jcb.201907098

May 07, 2020



Our paper on STIM1-Orai interactions has been published in JCS. It suggests a sequential binding model, in which STIM1 is first recruited to Orai through the CT; it then binds to Orai-NT for channel gating. Congratulations Liling and Fuyun!

Link: https://jcs.biologists.org/content/133/8/jcs239491

April 29, 2020



Our paper on structural and functional analysis of the inner mitochondrial fusion protein Mgm1 has been published in PNAS. It reveals a novel mode for homotypic membrane fusion. Congratulations Yuanbo!

Link: https://www.pnas.org/content/117/8/4061


February 25, 2020