Lab news

Our paper on OPA1-MGD structure has been published in JCB. It sheds light on its dimerization that is physiologically important and provides an explanation for pathogenic mutations. Congratulations Jinghua!

Link: https://doi.org/10.1083/jcb.201907098


Our paper on STIM1-Orai interactions has been published in JCS. It suggests a sequential binding model, in which STIM1 is first recruited to Orai through the CT; it then binds to Orai-NT for channel gating. Congratulations Liling and Fuyun!

Link: https://jcs.biologists.org/content/133/8/jcs239491


Our paper on structural and functional analysis of the inner mitochondrial fusion protein Mgm1 has been published in PNAS. It reveals a novel mode for homotypic membrane fusion. Congratulations Yuanbo!

Link: https://www.pnas.org/content/117/8/4061